8 Best Glycine Supplements for Health

With its versatile benefits, glycine is becoming increasingly popular as a key part of many people’s daily nutrition regimen. But how do you choose the best glycine supplement among the countless options on the market? Today’s article will provide the answer by reviewing and selecting the 8 best glycine supplements for health currently available.

Comparison Table of Best Product 

How We Choose Best Glycine Supplements?

Purity

High-quality glycine should have a high level of purity, meet safety standards, and be free from unnecessary additives or harmful ingredients. You can easily check the product’s purity by reviewing the ingredient information on the usage instructions label.

Efficacy

The effectiveness of glycine also depends on how the body absorbs and processes it. However, you can ensure this criterion by choosing products that have been proven to improve sleep quality, support joint health, and enhance overall well-being.

Dosage

Depending on individual needs and health conditions, each person may require a different amount of glycine supplementation. However, in general, products on the market typically recommend a dosage of about 3 to 5 grams per day for adults【2】.

Price

Price is also an important factor. I will compare and evaluate the products so you can make a choice that balances quality and reasonable pricing.

8 Best Glycine Supplements for Health

Vinatura GLYNAC 1000MG – Glycine & NAC | 24.89 USD | Best for Aging

Vinatura GLYNAC 1000MG – Glycine & NAC

Why Do We Choose It?

GLYNAC is a supplement containing 600 mg of NAC and 400 mg of Glycine, supporting detoxification, boosting energy, and providing essential components for natural glutathione synthesis. This product supplies vital antioxidants that help protect cells from oxidative stress and maintain overall cellular health, contributing to longevity for both men and women.

Customer Thomas Fournier shares: “I find this to be a solid addition to my supplement regimen. The combination of NAC and Glycine feels like a strong boost to my antioxidant levels. While the effects didn’t come immediately, I noticed a gradual improvement in my energy and overall vitality… I would recommend it to anyone looking to enhance their antioxidant capacity and support cellular health.”

I would recommend it to anyone looking to enhance their antioxidant capacity and support cellular health

Pros

• Powerful antioxidant properties that help maintain youthful vitality and overall immune health.
• Tested by a reputable third-party organization in the United States.
• Free from soy, tree nuts, wheat, and dairy, making it suitable for vegetarians.
• Carefully packaged for protection.

Cons

• The sulfur content in NAC can give the product a slightly unpleasant odor.

Nutricost Glycine Powder 1lb – Non-GMO, Gluten Free | 20.85 USD | Best for Sleep

Nutricost Glycine Powder 1lb – Non-GMO, Gluten Free

Why Do We Choose It?

Nutricost Glycine Powder 1lb – Non-GMO, Gluten-Free is a glycine powder product manufactured in a GMP-certified, FDA-registered facility. It is non-GMO, gluten-free, and has a naturally mild sweet taste, making it suitable for both vegetarians and those on a keto diet. The primary benefit of Nutricost Glycine is to improve sleep quality for both men and women.

Phillip, a user of the product, left a review on Amazon stating: “This product has been a game changer for me. It has improved my skin, nails, sleep quality, energy, and relaxation. One of the best supplements I’ve ever tried.”

Pros

• Includes a scoop for convenient use.
• Has a pleasant aroma and a refreshing, slightly sweet taste similar to sugar.

Cons

• Some users have not noticed the product’s effectiveness.
• There have been instances where residue remains after mixing it with water.

NOW Foods Supplements, Glycine 1,000 mg Free-Form | 16.99 USD | Best for Neurotransmitter Support 

NOW Foods Supplements, Glycine 1,000 mg Free-Form

Why Do We Choose It?

NOW Foods Supplements, Glycine 1,000 mg Free-Form is a dietary supplement produced in a GMP-certified facility and labeled according to U.S. standards. Its primary benefit is functioning as a neurotransmitter in the brain, facilitating nerve impulses to help maintain healthy sleep. This product is suitable for individuals of all backgrounds, providing support for restful sleep and overall wellness.

User Catherine Morland from the U.S. shares: “This product really works for me. I take 2-3 capsules before bed and can sleep continuously for 7 hours, whereas before, I completely struggled with that.”

Pros

• Promotes relaxation and comfort before bedtime.
• Provides a refreshing feeling upon waking.

Cons

• The capsules can be difficult to swallow and may get stuck in the throat, so use them with caution and keep them out of reach of children.

Life Extension Glycine, 1000 mg, Amino Acid Gluten-Free, Non-GMO, Vegetarian, 100 Capsules | 12.00 USD | Best for Sleep

Life Extension Glycine, 1000 mg, Amino Acid Gluten-Free, Non-GMO, Vegetarian, 100 Capsules

Why Do We Choose It?

Life Extension Glycine is designed to improve sleep quality by calming the brain, promoting relaxation, and helping you fall asleep more quickly. With a potent dose of 1,000 mg, this supplement provides a higher concentration of glycine compared to other products, maximizing its effectiveness for the body. Suitable for both men and women, Life Extension Glycine offers a powerful solution to enhance rest and overall well-being.

Avid, a user on Amazon, shares: “After years of struggling with insomnia, this product has proven effective for me. I fall asleep faster and stay asleep longer, waking up refreshed in the morning. I haven’t experienced any side effects and will continue using this product.”

Pros

• High-dose Glycine with powerful benefits.
• Non-GMO, gluten-free, suitable for vegetarians.

Cons

• Pregnant or breastfeeding women, as well as individuals undergoing medical treatment, should consult a doctor before using this product.

THORNE Glycine – Amino Acid | 27.00 USD | Best for Relaxation, Detoxification, and Muscle Function

THORNE Glycine – Amino Acid

Why Do We Choose It?

THORNE Glycine – Amino Acid is a supplement that supports relaxation, detoxification, and muscle function. Made with the purest ingredients, Thorne is free from gluten and common allergens, making it suitable for all users. Additionally, the brand is committed to safety standards, earning the trust of many consumers for its quality and effectiveness.

One of those users, Dzuz, left the following review: “Since I started taking this product in the evening, I average waking up only 1 or 2 times during the night, which is unbelievable… My life has completely changed; when I wake up, I feel like I’ve had deep, restful sleep.”

Pros

• Rated as one of the most effective supplements for the body.
• The packaging is easy to open, has no unpleasant taste, and is easy to swallow.

Cons

• It is advisable to take it a few hours before bedtime, as using it right before sleep may result in feeling groggy upon waking.

Micro Ingredients Glycine Powder, 1KG (2.2 Pounds), Glycine 1000 mg Per Serving | 27.50 USD | Best for Restful Sleep and Neurotransmitter

Micro Ingredients Glycine Powder, 1KG (2.2 Pounds), Glycine 1000 mg Per Serving

Why Do We Choose It?

Micro Ingredients Glycine Powder, made in the USA, is a non-GMO supplement designed to promote restful sleep and support neurotransmission for both men and women. Its easily dissolvable powder form allows for seamless mixing into shakes, smoothies, or other nutritional recipes, offering a convenient way to enhance your health routine with superior effectiveness.

User James J. Coffey shared, “I am over 70 years old and still use this product every day; it seems to help me a lot. This is also an affordable form of glycine that maintains quality.”

Pros

• Affordable price, convenient and economical packaging.
• Includes a scoop for measuring the dosage for each use.

Cons

• Some reviews indicate that they received the wrong measuring scoop or that the product had brown spots.

BulkSupplements.com Glycine Powder – Glycine Supplements, Glycine 3000mg – Glycine Amino Acid Supplement, Pure & Gluten Free | 22.76 USD | Best for Neurotransmitter Production

BulkSupplements.com Glycine Powder – Glycine Supplements, Glycine 3000mg – Glycine Amino Acid Supplement, Pure & Gluten Free

Why Do We Choose It?

BulkSupplements.com Glycine Powder is a versatile product suitable for all individuals, whether you’re an athlete or someone looking to maintain overall health. Its unflavored powder form allows for easy incorporation into food or drinks, providing an effective way to ensure your daily intake of glycine for optimal support.

User Sheetal Sura shared, “I was recommended this product by my doctor, and I find it effective in helping me sleep better. Surprisingly, it also enhances the taste and sweetness of my matcha.”

Pros

• Contains all essential nutrients to enhance your overall health.
• It can be easily blended with various smoothie recipes or other foods.

Cons

• No measuring spoon is provided for accurate dosage.

Metabolic Maintenance Glycine Powder | 35.00 USD | Best Powder for Calm Support, Liver Detoxification, Joint Health & Collagen Production

Metabolic Maintenance Glycine Powder

Why Do We Choose It?

Metabolic Maintenance Glycine Powder is a premium glycine supplement that helps regulate delta brain waves, promoting deep, restorative sleep so you wake up energized and refreshed. In addition to improving sleep quality, this product supports liver function, offers antioxidant protection, and enhances bone and joint health, making it an excellent choice for those looking to maintain an active and healthy lifestyle for both men and women.

User Nichole shares her experience: “My therapist recommended this product to help improve my sleep quality. I fell asleep within 10 minutes of taking it, and it doesn’t leave me feeling groggy when I wake up.”

Pros

• Effectively promotes sleep for most users.
• Convenient for travel or easy to carry in your handbag.

Cons

• Unclear serving size can lead to confusion for users.

What is the Best Glycine Supplement for Health?

After analyzing factors such as price, functionality, and user ratings, it’s clear that Vinatura GLYNAC 1000MG – Glycine & NAC stands out among other products. Not only does it provide a rich amount of glycine, but it also combines it with NAC, creating a complete formula that enhances overall health.

With an excellent balance between quality and price, Vinatura GLYNAC has gained trust and high appreciation in the market.

Glycine Supplements Buying Guide

Brand Reputation

To select a quality Glycine supplement, it’s best to prioritize products from well-established brands with a long history of development. The more reputable the brand, the more thoroughly the product is tested, and the more reviews it has from previous users.

Third-party Testing and Certifications

Don’t forget to check for third-party testing information and certifications (GMP) on the product packaging or website. Products with these two factors usually ensure quality, safety, and reliability for long-term health use.

Form

Glycine is available in two common forms: powder or tablets. Each form has its own advantages and disadvantages, making them suitable for different individuals. You should choose the form that best fits your needs and habits to ensure the most flexible use.

Review

Real user reviews are always a valuable source of information to consider before purchasing a product, especially health supplements. Therefore, take the time to read through user reviews to gain a better understanding of the product. Sometimes, you might even discover information about unwanted side effects or other services that could be useful.

Ingredient

You should choose glycine supplements that meet standard ingredient requirements with a high level of purity, free from harmful additives or gluten. This information is typically clearly displayed on the ingredient label or packaging, allowing you to easily assess the quality and safety of the product.

FAQs about Glycine Supplements

What is glycine supplement used for?

Glycine supplements are commonly used to help improve sleep, reduce stress, and enhance the functioning of the nervous system for users [1].

Is it safe to take glycine supplements every day?

The answer is yes, glycine is a safe supplement for daily use when taken at the recommended dosage of 3-5g per day [2]. However, if you are being treated for other health conditions, you should be cautious when combining it with other supplements, as there may be a risk of unwanted side effects.

Who should not take glycine?

Individuals with liver or kidney conditions, or those with a history of allergies to glycine, should be cautious when using glycine supplements. To ensure safety, it’s best to consult a doctor before planning to use glycine to improve health.

What are the symptoms of low glycine?

Glycine deficiency can be easily recognized by the following symptoms: fatigue, difficulty sleeping, frequent awakenings during the night, and decreased nervous system function.

What does glycine do in the body?

Glycine plays a role in protein synthesis, which helps improve sleep, reduce stress, support nervous system function, and protect joint health [1].

How much glycine should I take per day?

The recommended dosage of Glycine is between 3 to 5 grams per day [2]. However, this dosage may vary depending on individual needs, health conditions, or professional advice.

Does glycine have side effects?

Currently, there are not many reports of Glycine causing serious side effects. However, individuals who are new to using it and are not accustomed to the dosage may experience mild discomfort in the abdominal area.

What foods are rich in glycine?

Natural foods rich in glycine include meat, fish, eggs, and dairy products. However, the glycine content in these foods is relatively low, so you may need to supplement your diet with additional glycine from dietary supplements.

What are the benefits of taking a glycine supplement?

Supplementing with glycine can help improve sleep, enhance joint health, support nervous system function, and boost overall well-being[1].

How much glycine should I take to improve my sleep?

To improve sleep, you might consider taking a dose of 1 to 3 grams of glycine a few hours before bedtime. This dosage can help ensure that you enjoy deep sleep without feeling groggy when you wake up the next morning.

Can glycine and melatonin be taken together to improve sleep?

The answer is yes; the combination of glycine and melatonin can help improve sleep by relaxing the body and regulating the sleep cycle.

What is the difference between glycine and glycinate supplements?

Glycinate is a form of glycine bound to minerals like magnesium. It is often used to improve nutrient absorption and reduce stomach irritation.

Conclusion

Supplementing with glycine not only provides significant health benefits but also serves as a golden key to improving sleep and supporting recovery and energy restoration after a long, stressful day at work. Be sure to prioritize high-quality glycine supplements to ensure the results will meet your expectations.

References

[1] An Update of the Promise of Glycine Supplementation for Enhancing Physical Performance and Recovery Sports 2024, 12(10), 265; https://doi.org/10.3390/sports12100265

[2] Glycine ingestion improves subjective sleep quality in human volunteers, correlating with polysomnographic changes Original Article Published: 28 July 2016 Volume 5, pages 126–131, (2007) https://link.springer.com/article/10.1111/j.1479-8425.2007.00262.x